I found it very hard to choose between 2012 and the Aussie 2014 setlists. I'll be able to comment properly on the 2016 Asian setlist after Friday's gig in Thailand.
For me, the biggest, most-noticeable difference is the opener. How the show kicks off is a big thing. I love love LOVED the 'Flash' / 'The Hero' opener at the couple of Hammersmith gigs I attended. It's just the perfect build-up and grand reveal.
Just behind it is the 2014 'Procession' / 'Now I'm Here' opener. What makes this one so close is the use of lights and colour that brings this one so close to the 2012 opener (in my opinion, of course!). The way they're utilised and when they're utilised, creates so much excitement for the audience at the end of the 'Procession' bit where the band on-stage make their presence known ... and this is still a matter of maybe 20 seconds before the big curtain is yanked up and the audience can actually see Brian, Roger, Adam, ect!
I'm sure being there as 'One Vision' starts as the opener would still be an awesome experience (I can't help but feel it was best left in 1986 though), and as for 'Seven Seas Of Rhye', I hope I'm wrong, but I see this as being the weaker opener of all the ones in recent memory. If not of all Queen / Queen+____ history.
Bring back 'Flash'/'Hero' for Friday!!